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Transforming Clinical Uncertainty into a Strategy for Safe Care

Managing uncertainty is a core skill in primary care and other frontline clinical specialties such as emergency medicine where patients frequently present with early, evolving or non-specific symptoms that do not fit clear diagnostic categories. Rather than eliminating uncertainty, safe practice depends on recognising it, communicating transparently with patients and colleagues, and managing risk over time.  This is especially important for serious illnesses that may initially present with vague or common symptoms where premature or inappropriate reassurance can delay diagnosis. An example is ovarian cancer which can present with symptoms such as abdominal pain and bloating; and where there is overlap with other, less serious illnesses such as irritable bowel syndrome/ Safe management in patients with such presentations begins with a structured clinical assessment that considers red flags, comorbidities and the patient’s clinical and social contexts; alongside an explicit acknowled...

Combining Clinical Practice with Research: What do I Need to Know?

 I was recently asked by the BMJ to offer comments for an article advising doctors how they could improve their research skills and get involved in research. Integrating research into a clinical career offers a pathway to professional fulfilment, intellectual growth, and the opportunity to influence patient care on a broader scale.  While the prospect of balancing clinical duties with academic pursuits can be daunting due to time constraints and the need for specialised skills, there are numerous entry points available for clinicians at every stage of their career. From early-career networking and trainee-led collaborations to structured fellowships and leadership roles in national trials, the research landscape is designed to accommodate various levels of involvement. By developing core competencies, seeking out mentorship, and identifying practical questions within their own daily practice, clinicians can successfully navigate the challenges of a dual career and contribute ...

A New Vaccination Plan for England Must Start with Reinvesting in General Practice

 The Parliamentary Health and Social Care Committee states that the Government’s vaccination strategy is ‘a failure’ and should be replaced with a new plan. Vaccination rates in the UK have been falling since around 2012 when pressures on GP services began to increase. A key part of the solution to improving childhood vaccination rates in not to create new services like “family hubs” but to invest in core general practice services to increase primary care capacity. This needs to be combined with greater incentives for childhood vaccination. A successful vaccination strategy must strengthen and not sideline general practice. Without substantial reinvestment in general practice and improved incentives, any new structures will struggle to reverse the long-term decline in childhood vaccination coverage in the UK. GPs provide continuity, trusted relationships, accurate records, recalls, and opportunistic vaccination; all of which are  essential for high uptake. When GP capacity is ...

Managing Complications of Overseas Medical Procedures: An Emerging Challenge for UK General Practices and Emergency Departments

General practitioners and emergency medicine doctors in the UK are increasingly encountering patients who return from overseas with complications following medical procedures. These cases can often be  challenging to manage. Frequently, there is limited or no access to operative notes, discharge summaries, or detailed information about the techniques and materials used, making clinical assessment and safe follow-up difficult. The complications themselves are often complex, including serious infections, wound breakdown, thromboembolic events, and implant-related problems. Many require urgent specialist input. GPs are typically the first point of contact and must manage patient distress, clinical uncertainty, and risk, while navigating referral decisions in the absence of clear guidance or established care pathways. For patients, the lower cost of surgical procedures overseas can be an appealing alternative to private care in the UK. However, this often comes at the expense of struct...

Embedding AI Error Detection Into Primary Care Safety Culture

 As artificial intelligence (AI) become increasingly embedded in routine healthcare - supporting tasks such as triage, documentation, interpretation of investigation, diagnosis and patient communication - it introduces new patient safety risks through incorrect outputs (“hallucinations”) that should be treated as safety errors rather than technical glitches. In our article in the Journal of Patient Safety , we argue that primary care must extend its established safety culture to AI by systematically detecting, classifying, reporting, and learning from AI-related errors using principles already applied to human error, such as audit, governance, and incident reporting.  We highlight evidence that AI-generated clinical text can contain omissions, fabrications, or unsafe recommendations that may not be apparent to clinicians and patients and that risk becoming “silent errors” in electronic health records. These errors can then contribute to cognitive offloading if clinicians over-...

The role of vaccination, infection control measures and early treatment in curbing the impact of flu

Influenza remains a major cause of preventable illness each winter and continues to place significant pressure on NHS general practices, urgent care services, and hospitals. This has been particularly evident this winter, with flu rates much higher than we would normally expect for this time of year.  As of mid-December 2025, UKHSA surveillance shows influenza positivity in primary-care sentinel samples running well above most pre-COVID seasons, and hospital and ICU admissions for confirmed influenza are rising sharply — especially among adults aged 65 and over and those with long-term medical conditions. In general practice, we see first-hand how flu can lead to severe complications, particularly in older adults, people with underlying conditions, and those who are immunocompromised. Vaccination remains the single most effective way to reduce the risk of severe illness, hospitalisation, and death from flu. Interim data for the 2025–26 season suggest that vaccination is already red...

Relevance Over Recall: Rethinking How AI Uses Clinical Data

Our article in the Journal of the Royal Society of Medicine argues that safe and effective AI in healthcare must incorporate mechanisms that emulate human judgement - down-weighting old, inaccurate or superseded information and prioritising what is recent, clinically relevant and reaffirmed - so that AI supports, rather than disrupts, high-quality patient care.  Clinicians constantly revise, reinterpret and filter past information so that only what is relevant, accurate and timely shapes present-day management decisions; medical records function as dynamic “working tools” rather than fixed archives. By contrast, many AI systems lack this capacity for selective forgetting and often treat all historical data as equally meaningful.  This can lead to outdated or low-confidence diagnoses being repeatedly resurfaced, persistent labels influencing clinical expectations, and irrelevant, long-resolved events cluttering summaries and decision-support outputs. Such indiscriminate recall...

Getting mental health diagnoses right without undermining access to care and disability rights

The UK government’s forthcoming review of mental health and neurodevelopmental diagnoses presents an opportunity to improve the healthcare and benefits system if the potential risks are averted. Rising rates of conditions such as ADHD, autism, and anxiety disorders have raised questions about whether we are seeing a genuine increase in need or greater awareness and possible over-diagnosis. A thoughtful, evidence-based review could help bring much-needed clarity. But if mishandled, it could deepen inequalities and undermine support for those who need it most. Done well, the review could improve diagnostic quality and reduce the postcode lottery that too often defines access to assessment and treatment. Clearer clinical standards and properly funded services would allow professionals to make more accurate diagnoses, shorten long waiting lists, and better match interventions to individuals’ needs. This is an outcome everyone should welcome. But the review must not become a vehicle for re...

Balancing Innovation and Affordability: The New UK Approach to Drug Pricing

The announcement of a new UK-US pharmaceuticals deal is an important change in the UK’s approach to how new medicines are evaluated, priced and adopted. Faster access to innovative treatments for conditions such as cancer will be welcomed by patients and professionals. The increased investment in medicines may also help the UK attract more clinical research.  However, the impact of the proposals will depend on implementation. Raising NICE’s cost-effectiveness thresholds will increase overall NHS spending on medicines. Without a corresponding investment in areas such as workforce, diagnostics and primary care, there is a risk that higher drug spending could divert resources from other parts of the NHS. A more flexible pricing environment could also reduce the UK’s future negotiating leverage with industry. Maintaining NICE’s independence will be essential to maintain both public and professional confidence in its decision-making. The changes could benefit patients and strengthen th...

Teaching medical trainees to see societal infrastructure as a clinical issue

In an article published in the journal Frontiers in Medicine , we argue that medical education must broaden its focus: rather than treating infrastructure such as housing, transportation, energy, water supply as only a public-health or social background issue, trainees should regard infrastructural deficiencies as direct clinical determinants of patient health.  We highlight concrete examples (e.g., missed appointments due to transport failures, disrupted dialysis from electricity outages, contaminated water causing toxicity) showing how infrastructure can precipitate or worsen clinical problems. We propose educational innovations: embedding infrastructure-related history-taking, case-based learning driven by infrastructural triggers, community placements in underserved areas, and interdisciplinary learning (with urban planners, engineers, public health) to equip future clinicians with “systems-citizen” skills and advocacy capability.  The goal is to reframe clinical practice ...

From Lloyd George Envelopes to Artificial Intelligence: The Evolution of Medical Records in Primary Care

I spoke to GP Registrars on the Imperial College GP Training Scheme about the evolution of medical records in primary care. This is a journey that mirrors the broader transformation of healthcare itself. The story begins in 1911 , with the introduction of the Lloyd George Envelope following the National Insurance Act. These brown paper envelopes (named after the then Chancellor and future Prime Minister, David Lloyd George), each containing a patient’s handwritten medical notes and printed correspondence, became the standard for decades. They were simple, portable, and remarkably durable but also limited by their physical nature. Searching for information meant literally leafing through these paper records, and continuity of care relied on legibility and the clinician’s diligence in recording. The late 20th century brought a revolution: the computerisation of general practice . Early adopters in the 1980s and 1990s began using systems like EMIS and Vision, digitising the record and ...

Rethinking NICE Cost-Effectiveness Thresholds: Implications for the NHS and UK Industrial Strategy

There has been recent discussion about the need to revise drug pricing frameworks within the United Kingdom's National Health Service (NHS), particularly amid the ongoing transatlantic trade frictions involving potential tariffs from the United States administration. Elevating the cost-effectiveness threshold applied by the National Institute for Health and Care Excellence (NICE) by 25 percent from its established range of £20,000 to £30,000 per quality-adjusted life year (QALY) would increase access for NHS patients to innovative treatments that were previously excluded on grounds of excessive cost relative to their clinical benefits.  However, this change would also put increased pressure on the NHS budget. It is difficult to quantify the extra spending that might result from a wider range of drugs becoming available for use in the NHS through this change but any extra spending on these treatments would have to be matched by reductions in spending on other health services. Effect...

The importance of coding Long Covid in electronic medical records

As the world continues to grapple with the aftermath of the COVID-19 pandemic, Long Covid has emerged as a significant public health challenge. Characterised by persistent symptoms like fatigue, brain fog, shortness of breath, and joint pain lasting weeks, months or even years after an infection, Long Covid affects millions globally. Yet, one major hurdle in understanding and addressing this condition is its under-recording in electronic medical records (EMRs). Accurate coding of Long Covid in EMRs is essential for studying its epidemiology, improving patient care, and managing its impact on healthcare systems and on societies. Electronic medical records are at the core of modern health systems and have largely replaced the more traditional paper-based records used by healthcare providers for many decades. Electronic medical records are used to track patient diagnoses, treatments, and clinical outcomes. When Long Covid is not properly coded, it becomes difficult to use this data to c...

Empowering medical students to manage polypharmacy

Polypharmacy, commonly defined as the concurrent use of five or more medications, is a growing challenge in modern healthcare, especially among older adults with multiple long-term conditions. While advances in medicine have improved disease management, they have also led to an unintended consequence: a rising medication burden that can harm patient well-being.  Our recent study published in Clinical Practice explores how reframing polypharmacy as a chronic condition can empower future doctors to manage it more effectively. For example, polypharmacy substantially increases the risk of adverse drug reactions (ADRs). This underscores the urgent need for a shift in how we approach medication management.  Traditional medical education focuses on treating individual diseases, often leading to prescribing cascades where one drug’s side effect triggers another prescription. This cycle complicates care and worsens outcomes. We designed a three-phase educational intervention for final-...

What makes a good doctor – and who gets to decide?

What Makes a Good Doctor? This is the question that Waseem Jerjes and I explore in the Journal of the Royal Society of Medicine . It is a key question that underpins the architecture of medical education, clinical practice, regulation, and professional identity. It cannot be answered by regulators, educators, or employers in isolation. It must be answered together – by doctors and patients – revisited throughout a career, and adapted as society and the profession change. Without that shared reflection, the danger is not simply disillusionment, but the erosion of the moral foundations of clinical work. As we enter an era when diagnosis will increasingly involve artificial intelligence and when performance metrics reward volume over value, reclaiming this question as a professional one is imperative. The integrity of our institutions – and of the practitioners within them – depends on reimagining excellence in inclusive, relational terms. A good doctor is not a flawless technician or a f...

Talking to Patients About Weight-Loss Drugs

The use of weight-loss drugs such as GLP-1 receptor agonists (e.g., semaglutide, tirzepatide) has increased rapidly in recent years. These drugs can help some people achieve significant weight reduction, but they are not suitable for everyone and require careful counselling before starting treatment. By discussing benefits, risks, practicalities, and  uncertainties, clinicians can help patients make informed, realistic decisions about their treatment. Key points to discuss with patients 1. Indications and eligibility These drugs are usually licensed for adults with a specific BMI. They should be used alongside lifestyle interventions such as dietary change, increased physical activity, and behaviour modification. 2. Potential side effects – some can be serious Common adverse effects include nausea, vomiting, diarrhoea, and abdominal discomfort. Less common but more serious risks include gallstones, pancreatitis and visual problems. Patients should know what to watch for a...

The NHS Emergency Care Plan underestimates the role of general practice

I welcome the Government’s commitment to expanding urgent care provision in community settings. This approach has the potential to ease pressure on emergency departments and enable ambulance services to focus more effectively on patients who require rapid assessment and conveyance. However, as I discuss in the BMJ , the current Emergency Care Plan underestimates the central role that NHS general practice can and should play. Primary care is often the first point of contact for patients with urgent needs, and with appropriate support, it can manage many conditions effectively without referral to other parts of the system. There is also a risk that investing in a wide array of separate interventions—such as urgent treatment centres, community response teams, and virtual wards—without clear coordination could further fragment care. This may reduce continuity, lead to duplication, and ultimately result in less efficient use of NHS resources. Direct investment in NHS general practice—partic...

Balancing Patient Safety and Human Rights: Implementing the Special Allocation Scheme in Primary Care

The Special Allocation Scheme (SAS) aims to protect NHS staff and other patients from individuals who are violent, aggressive, or pose a serious threat, while at the same time ensuring that these patients continue to receive essential primary care services in a secure environment. The decision to refer a patient to the Special Allocation Scheme is a significant one and rightly requires careful clinical and ethical consideration. However, in practice, such decisions often need to be made rapidly and under stressful or unpredictable circumstances, such as following a serious verbal or physical assault on a member of staff. Updated guidance from NHS England and the additional requirements introduced by some Integrated Care Boards (ICBs), including the need for written confirmation that all alternative approaches have been considered, are well-intentioned. These measures are designed to ensure that referrals to the Special Allocation Scheme are proportionate, lawful, and respectful of pat...

Reclaiming the primary care consultation for patients and clinicians: is AI-enabled ambient voice technology the answer?

 Our recent article in the Journal of the Royal Society of Medicine discusses the potential role of AI-enabled ambient voice technology in healthcare and the implications for doctors and patients. While interest in ambient voice technology , particularly in primary care, continues to grow, evidence regarding its feasibility, acceptability and real-world impact in primary care remains limited. This includes data on cost, staff training and implementation (including integration with current electronic medical record systems).  Questions also remain about how ambient voice technology  handles complex consultations, including with non-native English speakers, and its broader integration into routine practice. As ambient voice technology  develops, further research is needed to assess its usability, acceptability, feasibility, cost-effectiveness and unintended effects on clinical interactions and decision-making. If demonstrated to be effective, ambient voice technology...

Why after 35 Years of NHS plans, treatment is still favoured over prevention?

The aims of the government’s 10 year health plan – such as the shift from prevention to cure – are not new and have been priorities in many other health plans over the last 35 years. The question we need to ask is why have previous plans failed in achieving these objectives? The short-term electoral cycle prioritises funding for immediate, visible hospital crises over long-term strategies whose benefits are not seen for years. This is compounded by a health system that is designed to reward the treatment of sickness, not the promotion of wellness.  The persistent fragmentation between the NHS, public health and social care, and pressures from an ageing population and widening health inequalities have created a reactive environment where long-term strategic goals are perpetually sacrificed to manage immediate demands. The UK government and NHS staff do not lack insight into what improves health. Unless we redesign the incentives, protect public‑health budgets and hold every departme...